Homepage - EF CLIF

Shaping the future of chronic liver disease together

We support clinical and translational research to address unmet needs in chronic liver failure

Our strategy

Latest news

Multi-ancestry genome-wide association study identifies gene variant linked to renal impairment in decompensated cirrhosis

16 October 2026

CHANCE study provides global evidence of survival benefit from liver transplantation in severe ACLF

1 October 2026

Plasma exchange improves short-term survival in patients with acute-on-chronic liver failure

25 August 2026

Events

9th CHANCE Investigator Meeting

29 May 2026 , Barcelona, Spain

EASL-CLIF Consortium General Assembly 2026

28 May 2026 , Barcelona, Spain

Gain access to data and samples through the Data Hub

Researchers are encouraged to submit their research proposals for access to our data platform

Join our advanced training course on hepatology research

Endorsed by University of Barcelona, our master program prepares professionals to lead innovation, contribute to international research networks, and drive better outcomes in liver care.

Fully online and flexible
Expert-led video lectures and curated readings
Interactive learning with clinical cases and applied assignments

EASL-CLIF Consortium predictive scores

CLIF-C predictive scores are sequentially used in patients admitted to hospital with acutely decompensated cirrhosis.

CLIF-C OF score is used to assess the function of six major organ systems for the diagnosis of acute-on-chronic liver failure (ACLF)
CLIF-C ACLF score provides accurate information in predicting risk of 28-day mortality in patients with ACLF
CLIF-C AD score provides accurate information in predicting risk of developing ACLF and 3-month mortality in patients without ACLF

CLIF-C score calculator

CLIF-C scores provide accurate prognostic information in patients with underlying cirrhosis, with and without ACLF

Research

Past and ongoing research projects. View research by topic.

Our network

We collaborate with leading tertiary care centers and university hospitals across the world.

Publications

List of scientific publications from past and ongoing research activities.

Our impact

Find out more about how we are contributing to help improve the quality of life of patients with chronic liver disease.