The problem

My main fields of interest are:

• Acute-on-chronic liver failure (ACLF) pathogenesis, prognosis, and critical care
• Bacterial infections in decompensated cirrhosis (epidemiological changes, prognostic impact, and preventive and therapeutic strategies)
• Liver support systems
• New indications for albumin therapy

The approach

Observational and interventional trials

Main discoveries and innovations

• Contributor to the development of new prognostic scores and futility criteria of ACLF
• Led first research team to report the growing increase in antibiotic resistance in cirrhosis and to suggest preventive and therapeutic strategies to mitigate