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The Data Management Center at the European Foundation for the Study of Chronic Liver Failure (EF CLIF) is expanding its scope to conduct large-scale observational studies and clinical trials of increasing complexity.
We are looking for a biostatistician to provide statistical expertise in the design of statistical analysis plans (SAPs) for research projects and clinical trials, referring to senior statistical experts where necessary. You will manage your own projects within your working schedule and apply a range of statistical methods to solve complex problems as part of a multidisciplinary team.
The candidate’s responsibilities include:
The successful candidate will join the Data Management Center, which coordinates all activities related to the development of clinical platforms, data cleansing processes, and biological sample management. The team is currently constituted by 4 members including bioinformaticians, statisticians, data managers, and the CTIO.
Throughout the data lifecycle, from collection and preservation to analysis and dissemination, the Data Management Center operates in accordance with the FAIR principles – making data findable, accessible, interoperable and reusable, applying the highest standards in clinical research and in compliance with the General Data Protection Regulation (GDPR).
The Data Management Center is based in the EF CLIF Headquarters in Barcelona, Spain, and serves as a resource for our members and collaborators in tertiary care university hospitals across the world, enabling access to relevant clinical and laboratory data, and specimens through a secure environment.
The Data Management Center plays an important role in the design and development of the databases and protocols for all EF CLIF sponsored studies, ensures good research data management, assists regional coordinator with protocol implementation, tracks specimen information, delivers remote training across study sites, and contributes to data analysis and manuscript preparation.
Moreover, the Data Management Center provides support in the study design and work planning of research project proposals, as well as bioinformatics and statistical expert consultation.
Professional experience
Education and training
Technical skills
Competences
Languages
We provide a highly stimulating environment and unique professional development opportunities tailored to our employees’ needs.
We welcome applicants regardless of age, disability, gender, religion or political beliefs.
Applications must include:
Applications must be sent out by email via efclif@efclif.com indicating reference STAT
Deadline: Please submit your applications by 20 September 2024
The European Foundation for the Study of Chronic Liver Failure (EF CLIF) is a private nonprofit organization which mission is to promote research and education in chronic liver disease with the aim to contribute to improving the quality of life and to increase the survival of patients with cirrhosis.
EF CLIF has made pioneering efforts in conducting a series of large, international prospective studies that have been instrumental in reclassifying the trajectory of patients with chronic liver failure and led to the clinical, prognostic and pathophysiological definition of the syndrome referred to as “acute-on-chronic liver failure” (ACLF) characterized by acute decompensation of cirrhosis, severe systemic inflammation, organ failures, and high short-term mortality.
Since its foundation in 2009, the European Association for the Study of the Liver (EASL) Chair supports research activities through the EASL-CLIF Consortium, a network of 120 tertiary level university hospitals in 30 European countries. The EASL Chair promotes research in liver disease in Europe through a collaborative effort aimed at furthering the knowledge and understanding of the mechanisms underlying cirrhosis and its complications. The EASL-CLIF Consortium provides the framework to conduct ancillary studies and clinical trials that will lead to evaluate new therapies in cirrhosis, establish diagnostic criteria, and identify predictors for the design of new prognostic scores for acute-on-chronic liver failure—to improve the quality of life and survival of current and future patients with cirrhosis.
The Grifols Chair promotes translational studies across centers throughout Europe and North America within the framework of the European Network for Translational Research (ENTR) with 21 centers in 7 countries. The Grifols Chair promotes research aimed at characterizing the mechanisms underlying the presence of systemic inflammation in patients with decompensation of cirrhosis and its role in the development of acute-on-chronic liver failure
More recently, the establishment of the Global Projects chapter has enabled to establish connections between healthcare professionals and experts over the world to further the understanding of the epidemiology and pathophysiology of ACLF. Through collaborative research, the Global Projects also aim to identify novel biomarkers and therapeutic targets in cirrhosis and develop guidelines that will contribute to minimize regulatory barriers and facilitate better outcomes and quality of life for patients with chronic liver disease worldwide.
EF CLIF also partners with industry to address unmet medical needs in cirrhosis and generate insights to drive innovative therapeutic solutions that can transform and revolutionize patient care.
The Data Management Center enables access to specimens and relevant clinical and laboratory data, and provides bioinformatics and statistical analysis expertise.
European Foundation for the Study of
Chronic Liver Failure
Travessera de Gràcia 11, 7th floor
08021 Barcelona, Spain
© European Foundation for the Study of Chronic Liver Failure 2024
