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Content published within the Highlights section on the European Foundation for the Study of Chronic Liver Failure’s News site is available under Creative Commons license CC BY 4.0 unless otherwise stated.

Showing 10 of 31 publications

20 June 2024

Findings from the CHANCE study urge the need for improved graft allocation policies

New insights on liver transplantation for patients with severe acute-on-chronic liver failure (ACLF) were presented at EASL Congress 2024 - the annual international conference organized by the European Association for the Study of the Liver (EASL) bringing together experts in hepatology to share the latest research, advancements, and clinical practices on liver disease.

30 April 2024

Standardizing metadata and sample processing in microbiome clinical studies

In a collaborative effort, the Human Microbiome Action (HMA) Consortium has completed a Delphi process to establish minimal requirements for clinical metadata and sample processing to improve the reproducibility of microbiome research.

20 April 2024

Interim results from the CHANCE study presented at ELITA Summit 2024

Key findings highlighted survival benefits and organ allocation challenges in liver transplantation for patients with severe acute-on-chronic liver failure (ACLF).

29 February 2024

LEOPARD kicks off to improve liver allocation with AI

European consortium launches ambitious initiative to revolutionize liver transplant allocation using artificial intelligence (AI)-driven predictive models, aiming to reduce waitlist mortality and harmonize transplant practices across Europe.

01 February 2024

CHANCE study enters phase 2 to define liver transplantation futility criteria in patients with severe ACLF

Three years after its launch, the CHANCE study is moving into a new operational phase focused on patients with most severe forms of acute-on-chronic liver failure (ACLF) at the time of listing for liver transplantation. This phase aims to determine the minimum threshold needed both for graft and patient survival after transplantation.

16 October 2023

EF CLIF researchers among the most cited scientists in the world

Six researchers affiliated to EF CLIF are listed in the world’s top 2% highly cited scientists ranking, a science-wide database of 100,000 top scientists that includes 22 scientific fields and 176 subfields.

10 October 2023

CHANCE celebrates the recruitment of its 1000th patient

Significant milestone in the first global prospective study analyzing intention-to-treat survival benefit of liver transplantation for patients with severe acute-on-chronic liver failure (ACLF) – a syndrome characterized by acute decompensation of cirrhosis associated with multisystem organ failure and high short-term mortality.

16 May 2023

A CHANCE for researchers to win a registration for The Liver Meeting 2023

We call all investigators in CHANCE to help us reach the 1000th patient milestone.

17 October 2022

The patient perspective

Today, it is widely recognized the role of patients in clinical research beyond their participation as research subjects. Patients' organizations continue evolving in their role of supporting patients and their families, advocating and publicly representing the collective identity of their members to raise awareness of their disease and influence health policymakers. More recently, the role of expert patient has emerged to input their unique experiences into research.

14 October 2022

A CHANCE for researchers to win a registration for the EASL Congress 2023

We are close to reaching 500 patients and we would like to celebrate this milestone with all our colleagues and collaborators in the CHANCE study.

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