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Content published within the Highlights section on the European Foundation for the Study of Chronic Liver Failure’s News site is available under Creative Commons license CC BY 4.0 unless otherwise stated.

Showing 10 of 124 publications

04 November 2024

New score helps predict liver cancer risk in patients with advanced chronic liver disease

Researchers develop an algorithm to improve early cancer detection and personalize screening schedules for patients with advanced chronic liver disease.

28 October 2024

Study links immune system alterations to progression of decompensated cirrhosis

Findings from a large cohort study reveal new insights into changes in blood levels of cytokines involved in key immune responses against a range of infectious threats. These changes, along with elevated neutrophil counts and reduced lymphocyte counts, were each associated with an increased risk of developing acute-on-chronic liver failure (ACLF), regardless of the presence of clinically apparent precipitants.

21 October 2024

6th DECISION General Assembly discusses progress on new combinatorial therapy and prognostic biomarkers for acutely decompensated cirrhosis

The meeting focused on novel combinatorial therapies, biomarker validation, and the translation of scientific discoveries into clinical applications.

05 September 2024

Pathways to advancing from discovery to clinical implementation of microbiome-based biomarkers

Expert consensus calls for standardization and collaboration to drive clinical implementation of measurable indicators derived from the composition or activity of microorganisms in the human body. These biomarkers can provide insights into health conditions, help diagnose diseases, predict treatment responses, or monitor disease progression by reflecting changes in the body's microbiome.

15 August 2024

Albumin boosts immune system function in patients with decompensated cirrhosis

New research reveals how albumin improves B cell function and enhances neutrophil antimicrobial capabilities, reducing infection risk in vulnerable patients.

23 July 2024

Job opportunity: Biostatistician

Reference: STAT

01 July 2024

Immunometabolic states associated with recovery in acute-on-chronic liver failure

New study links distinct immune cell profiles to acute-on-chronic liver failure (ACLF) outcomes.

28 June 2024

New tool identifies patient subgroups for personalized management of acutely decompensated cirrhosis

ClustALL, a newly developed stratification method provides insights in understanding differences among patients with acutely decompensated cirrhosis showing potential for clinical applications.

20 June 2024

Findings from the CHANCE study urge the need for improved graft allocation policies

New insights on liver transplantation for patients with severe acute-on-chronic liver failure (ACLF) were presented at EASL Congress 2024 - the annual international conference organized by the European Association for the Study of the Liver (EASL) bringing together experts in hepatology to share the latest research, advancements, and clinical practices on liver disease.

15 June 2024

New center joins the EASL-CLIF Consortium: Meet the center coordinator and their team

The EASL-CLIF Consortium Steering Committee met on 6 June 2024 in Milan, Italy, during the EASL Congress 2024, to assess new applications by candidate centers as we continue growing our network of leading university hospitals and tertiary care centers across Europe.

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