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Advancing knowledge in chronic liver disease through evidence-based research.
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Showing 10 of 159 papers

Autophagy-related activation of hepatic stellate cells reduces cellular miR-29a by promoting its vesicular secretion

Yu X, Elfimova N, Müller M, Bachurski D, Koitzsch U, Drebber U, Mahabir E, Hansen HP, Friedman SL, Klein S, Dienes HP, Hösel M, Buettner R, Trebicka J, Kondylis V, Mannaerts I, Odenthal M.

Cell Mol Gastroenterol Hepatol 2022, 13(6): 1701–1716

DOI: 10.1016/j.jcmgh.2022.02.013

Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure

Zhang IW, Curto A, López-Vicario C, Casulleras M, Duran-Güell M, Flores-Costa R, Colsch B, Aguilar F, Aransay AM, Lozano JJ, Hernández-Tejero M, Toapanta D, Fernández J, Arroyo V, Clària J.

J Hepatol 2022, 76(1): 93–106

DOI: 10.1016/j.jhep.2021.08.009

PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLF

Li J, Liang X, Jiang J, Yang L, Xin J, Shi D, Lu Y, Li J, Ren K, Hassan HM, Zhang J, Chen P, Yao H, Li J, Wu T, Jin L, Ye P, Li T, Zhang H, Sun S, Guo B, Zhou X, Cai Q, Chen J, Xu X, Huang J, Hao S, He J, Xin S, Wang D, Trebicka J, Chen X, Li J; Chinese Group on the Study of Severe Hepatitis B (COSSH).

Gut 2022, 71(1): 163–175

DOI: 10.1136/gutjnl-2020-323395

The role of RIPK1 mediated cell death in acute on chronic liver failure

Kondo T, Macdonald S, Engelmann C, Habtesion A, Macnaughtan J, Mehta G, Mookerjee RP, Davies N, Pavesi M, Moreau R, Angeli P, Arroyo V, Andreola F, Jalan R.

Cell Death Dis 2021, 13(1): 5

DOI: 10.1038/s41419-021-04442-9

Granulocyte-colony stimulating factor (G-CSF) to treat acute-on-chronic liver failure: A multicenter randomized trial (GRAFT study)

Engelmann C, Herber A, Franke A, Bruns T, Reuken P, Schiefke I, Zipprich A, Zeuzem S, Goeser T, Canbay A, Berg C, Trebicka J, Uschner FE, Chang J, Mueller T, Aehling N, Schmelzle M, Splith K, Lammert F, Lange CM, Sarrazin C, Trautwein C, Manns M, Häussinger D, Pfeiffenberger J, Galle PR, Schmiedeknecht A, Berg T.

J Hepatol 2021, 75(6): 1346–1354

DOI: 10.1016/j.jhep.2021.07.033

Primary biliary cholangitis has the highest waitlist mortality in patients with cirrhosis and acute on chronic liver failure awaiting liver transplant

Singal AK, Wong RJ, Jalan R, Asrani S, Kuo YF.

Clin Transplant 2021, 35(12): e14479

DOI: 10.1111/ctr.14479

Variceal bleeding has increased mortality compared to nonvariceal bleeding only in males

Erasmus HP, Bektas R, Orland K, Trifonova S, Gu WY, Uschner FE, Brol MJ, Chang J, Praktiknjo M, Strassburg CP, Trebicka J, Jansen C.

Eur J Gastroenterol Hepatol 2021, 33(1S Suppl 1): e94–e101

DOI: 10.1097/MEG.0000000000001964

Trends and the course of liver cirrhosis and its complications in Germany: Nationwide population-based study (2005 to 2018).

Gu W, Hortlik H, Erasmus HP, Schaaf L, Zeleke Y, Uschner FE, Ferstl P, Schulz M, Peiffer KH, Queck A, Sauerbruch T, Brol MJ, Rohde G, Sanchez C, Moreau R, Arroyo V, Zeuzem S, Welsch C, Trebicka J.

Lancet Reg Health Eur 2021, 12: 100240

DOI: 10.1016/j.lanepe.2021.100240

Untargeted lipidomics uncovers lipid signatures that distinguish severe from moderate forms of acutely decompensated cirrhosis

Clària J, Curto A, Moreau R, Colsch B, López-Vicario C, Lozano JJ, Aguilar F, Castelli FA, Fenaille F, Junot C, Zhang I, Vinaixa M, Yanes O, Caraceni P, Trebicka J, Fernández J, Angeli P, Jalan R, Arroyo V.

J Hepatol 2021, 75(5): 1116–1127

DOI: 10.1016/j.jhep.2021.06.043

Liver transplantation for patients with acute-on-chronic liver failure (ACLF) in Europe: Results of the ELITA/EF-CLIF collaborative study (ECLIS)

Belli LS, Duvoux C, Artzner T, Bernal W, Conti S, Cortesi PA, Sacleux SC, Pageaux GP, Radenne S, Trebicka J, Fernandez J, Perricone G, Piano S, Nadalin S, Morelli MC, Martini S, Polak WG, Zieniewicz K, Toso C, Berenguer M, Iegri C, Invernizzi F, Volpes R, Karam V, Adam R, Faitot F, Rabinovich L, Saliba F, Meunier L, Lesurtel M, Uschner FE, Fondevila C, Michard B, Coilly A, Meszaros M, Poinsot D, Schnitzbauer A, De Carlis LG, Fumagalli R, Angeli P, Arroyo V, Jalan R; ELITA/EF-CLIF working group.

J Hepatol 2021, 75(3): 610–622

DOI: 10.1016/j.jhep.2021.03.030